Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
Shinoda K, Li R, Rezk A, Mexhitaj I, Patterson KR, Kakara M, Zuroff L, Bennett JL, von Büdingen HC, Carruthers R, Edwards KR, Fallis R, Giacomini PS, Greenberg BM, Hafler DA, Ionete C, Kaunzner UW, Lock CB, Longbrake EE, Pardo G, Piehl F, Weber MS, Ziemssen T, Jacobs D, Gelfand JM, Cross AH, Cameron B, Musch B, Winger RC, Jia X, Harp CT, Herman A, Bar-Or A.
Shinoda K, et al.
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2207291120. doi: 10.1073/pnas.2207291120. Epub 2023 Jan 12.
Proc Natl Acad Sci U S A. 2023.
PMID: 36634138
Free PMC article.
Similarly, this disease activity did not correlate with early reconstituting B cells, which were predominantly transitional CD19(+)CD24(high)CD38(high) with a more anti-inflammatory profile. ...
Similarly, this disease activity did not correlate with early reconstituting B cells, which were predominantly transitional CD19(+)CD …